This publication presents an overview of the 2000 survey of 8th, 10th, and 12th grade students, with a particular emphasis on recent trends in the use of various licit and illicit drugs. It also shows trends in the levels of perceived risk and personal disapproval associated with each drug, which this study has shown to be particularly important in explaining trends in use. The first section presents trends in the overall proportions of students at each grade level reporting illicit drug use. A separate section is then presented for each class of drugs. These sections contain graphs showing trends in past-year use. They also show trends in perceived risk, disapproval, and perceived availability of marijuana, inhalants, LSD, cocaine, crack cocaine, amphetamines, heroin, tranquilizers, barbiturates, club drugs, alcohol, cigarettes, smokeless tobacco, and steroids. Key findings show that the overall illicit drug use among teens remained steady in 2000 in all three grades as well as for specific drugs such as marijuana, amphetamines, hallucinogens other than LSD, tranquilizers, barbiturates, and alcohol. (Contains 9 tables.) (JDM)