Objectives: To estimate the quantity of informal care associated with neuropsychiatric symptoms in older adults with cognitive impairment. Design: Cross-sectional analysis. Setting: The Aging, Demographics, and Memory Study. Participants: A sample (n=450) of adults aged 71 years and older with cognitive impairment drawn form the Health and Retirement Study. Measurements: The presence of neuropsychiatric symptoms… Continue reading Caregiver Burden and Neuropsychiatric Symptoms in Older Adults With Cognitive Impairment: The Aging, Demographics, and Memory Study (ADAMS)

: Results from clinical samples suggest low serum albumin may be associated with cognitive impairment, though evidence from population-based studies is inconclusive. Participants were 1,752 adults (699 men and 1,053 women) aged 65 years and over from the Health Survey for England 2000, a nationally representative population-based study. Cognitive impairment was assessed using the Abbreviated… Continue reading Serum Albumin Concentration and Cognitive Impairment

Background: Research in novel therapies for Alzheimer disease (AD) relies on persons with AD as research subjects. Because AD impairs decisional capacity, informed consent often must come from surrogates, usually close family members. But policies for surrogate consent for research remain unsettled after decades of debate. Methods: We designed a survey module for a random… Continue reading Surrogate consent for dementia research: A national survey of older Americans

Background: There are barriers to acute stroke care in minority groups as well as a higher incidence of ischemic stroke when compared with non-Hispanic whites. Objective: To estimate the future economic burden of stroke in non-Hispanic whites, Hispanics, and African Americans in the United States from 2005 to 2050. Methods: We used U.S. Census estimates… Continue reading Projected costs of ischemic stroke in the United States