Polymorphisms in Renal Ammonia Metabolism Genes Correlate With 24-Hour Urine pH

Urine pH is critical for net acid and solute excretion, but the genetic factors that contribute to its regulation are incompletely understood. We tested the association of single nucleotide polymorphisms (SNPs) from 16 genes related to ammonia (NH3) metabolism (15 biological candidates selected a priori, 1 selected from a previous genome-wide associated study analysis) to… Continue reading Polymorphisms in Renal Ammonia Metabolism Genes Correlate With 24-Hour Urine pH